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Correction: CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma
Journal of Experimental & Clinical Cancer Research volume 43, Article number: 320 (2024)
The Original Article was published on 29 July 2020
Correction: J Exp Clin Cancer Res 39, 145 (2020)
Following publication of the original article [1], the author identified errors in Fig. 8. The western blot bands of Cathepsin B in Fig. 8F and the representative image for the CD147OE + shCTSB group in Fig. 8G were erroneously assembled.
The corrected figure is presented below:
Incorrect Fig. 8
CD147 promotes cathepsin B via β-catenin signaling. a-b. Western blot analysis of indicated proteins in Huh-7 (a) and HepG2 (b) cells transfected with indicated constructs. c-d. Quantitative real-time PCR analysis of CTSB expression in Huh-7 (c) and HepG2 (d) cells transfected with indicated constructs. *** p < 0.0001, one-way ANOVA. e-f. Western blot analysis of indicated proteins in Huh-7 (b) and HepG2 (f) cells transfected with indicated siRNAs or treated with TWS119. G. Metastasis assay by intra-splenic injection of indicated cells in nude mice. Livers were excised for examination (left panel). Graph shows quantitative analysis of intrahepatic metastasis. * p < 0.05, ** p < 0.01, one-way ANOVA. h. Kaplan-Meier survival curves of HCC patients stratified into double positive- and double negative-expression of CD147 and cathepsin B according to immunohistochemical staining. i. Schematic representation of the major mechanisms of CD147 regulating collective invasion in hepatocellular carcinoma
Correct Fig. 8
CD147 promotes cathepsin B via β-catenin signaling. a-b. Western blot analysis of indicated proteins in Huh-7 (a) and HepG2 (b) cells transfected with indicated constructs. c-d. Quantitative real-time PCR analysis of CTSB expression in Huh-7 (c) and HepG2 (d) cells transfected with indicated constructs. *** p < 0.0001, one-way ANOVA. e-f. Western blot analysis of indicated proteins in Huh-7 (b) and HepG2 (f) cells transfected with indicated siRNAs or treated with TWS119. G. Metastasis assay by intra-splenic injection of indicated cells in nude mice. Livers were excised for examination (left panel). Graph shows quantitative analysis of intrahepatic metastasis. * p < 0.05, ** p < 0.01, one-way ANOVA. h. Kaplan-Meier survival curves of HCC patients stratified into double positive- and double negative-expression of CD147 and cathepsin B according to immunohistochemical staining. i. Schematic representation of the major mechanisms of CD147 regulating collective invasion in hepatocellular carcinoma
The corrections do not affect the overall results, discussion, or conclusion of the article.
References
Wang SJ, Chao D, Wei W, et al. CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma. J Exp Clin Cancer Res. 2020;39:145. https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-020-01647-2.
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Wang, SJ., Chao, D., Wei, W. et al. Correction: CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma. J Exp Clin Cancer Res 43, 320 (2024). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-024-03246-x
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DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-024-03246-x