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Correction: Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN

Journal of Experimental & Clinical Cancer Research volume 44, Article number: 34 (2025) Cite this article

The Original Article was published on 12 March 2018

Correction: J Exp Clin Cancer Res 37, 54 (2018)

https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-018-0711-9


Following the publication of the original article [1], the authors identified errors in Figure 7G and Supplementary Material Figure S3.

  • Figures 7G – Invasion result of NC-NC(G25)

  • Figure S3 – Invasion result of shNC(G25)

The correct figures are given below.

Incorrect Fig. 7 

Fig. 7
figure 1

PTEN plays an important role in SCD1-induced migration and invasion of CRC cells. a, b Representative Western blot and quantification data of PTEN proteins of OA-treated HCT116 (a) and Caco2 (b) cells. c Representative Western blot and quantification data of PTEN in HCT116 cells transfected with siRNAs for PTEN (si1 and si2) or Caco2 cells ectopically expressing PTEN. d Representative photographs of transwell assays of shSCD1 or shNC-transfected HCT116 after being transfected with PTEN siRNAs (siPTEN) or negative control scramble siRNAs (siNC). The scale bar is 100 μm. e, f Histograms show the numbers of migrated (e) and invasive (f) HCT116 cells. g Transwell assay of SCD1 overexpression Caco2 cell lines after ectopically expressing PTEN. The scale bar is 100 μm. h, i Histograms show the number of migrated (h) and invasive (i) Caco2 cells

Full size image

Correct Fig. 7 

Fig. 7
figure 2

PTEN plays an important role in SCD1-induced migration and invasion of CRC cells. a, b Representative Western blot and quantification data of PTEN proteins of OA-treated HCT116 (a) and Caco2 (b) cells. c Representative Western blot and quantification data of PTEN in HCT116 cells transfected with siRNAs for PTEN (si1 and si2) or Caco2 cells ectopically expressing PTEN. d Representative photographs of transwell assays of shSCD1 or shNC-transfected HCT116 after being transfected with PTEN siRNAs (siPTEN) or negative control scramble siRNAs (siNC). The scale bar is 100 μm. e, f Histograms show the numbers of migrated (e) and invasive (f) HCT116 cells. g Transwell assay of SCD1 overexpression Caco2 cell lines after ectopically expressing PTEN. The scale bar is 100 μm. h, i Histograms show the number of migrated (h) and invasive (i) Caco2 cells

Full size image

Incorrect Figure S3

figure a

Additional file 3: Figure S3 Effect of glucose on SCD1-induced migration and invasion ability of SW116 cells. (A) Representative photographs of transwell assays of shSCD1 or shNC-transfected SW116 cells after glucose treatment. The scale bar is 100 μm. (B, C) Histograms show the numbers of migrated (B) and invasive (C) SW116 cells. (TIFF 1277 kb)

Correct Figure S3

figure b

Additional file 3: Figure S3 Effect of glucose on SCD1-induced migration and invasion ability of SW116 cells. (A) Representative photographs of transwell assays of shSCD1 or shNC-transfected SW116 cells after glucose treatment. The scale bar is 100 μm. (B, C) Histograms show the numbers of migrated (B) and invasive (C) SW116 cells. (TIFF 1277 kb)

The corrections do not compromise the validity of the conclusions and the overall content of the article.

Reference

  1. Ran H, Zhu Y, Deng R, et al. Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN. J Exp Clin Cancer Res. 2018;37:54. https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-018-0711-9.

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Author notes

  1. Hui Ran, Yemin Zhu and Ruyuan Deng contributed equally to this work.

Authors and Affiliations

  1. Department of Endocrinology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665, Kong Jiang Road, Shanghai, 200092, China

    Hui Ran, Ruyuan Deng, Qi Zhang & Qing Su

  2. Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, 280 S. Chongqing Road, Shanghai, 200025, China

    Yemin Zhu, Ming Feng, Jie Zhong, Shuhai Lin & Xuemei Tong

  3. Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 100, Haining Road, Shanghai, 200080, China

    Xisheng Liu

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  1. Hui Ran
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Corresponding authors

Correspondence to Xuemei Tong or Qing Su.

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Ran, H., Zhu, Y., Deng, R. et al. Correction: Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN. J Exp Clin Cancer Res 44, 34 (2025). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-025-03300-2

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  • DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-025-03300-2

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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