- Correction
- Open access
- Published:
Correction: MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation
Journal of Experimental & Clinical Cancer Research volume 44, Article number: 4 (2025)
The Original Article was published on 24 August 2023
Correction: J Exp Clin Cancer Res42, 219 (2023)
Following the publication of the original article [1], the authors identified an error in Fig. 7D. The image presented for the MKRN1 f/f group (IHC staining of TGF-β1) was inadvertently incorrect due to an oversight during figure preparation.
The correct figure is presented below:
Correct Fig. 7D
MKRN1 promotes tumour proliferation and metastasis in vivo. A Comparative graph showing the number of intestinal lesions in the MKRN1 [+/+] and MKRN1 [f/f ] groups. B Haematoxylin–eosin (H&E) staining of the intestine of both groups of mice (scale bar: 100 μm). C H&E staining of the liver in the two groups of mice (scale bar: 100 μm; scale bar: 20 μm). D IHC staining for Ecadherin, MKRN1, SNIP1, and TGFβ1 in the intestinal tissues of the two groups of mice (scale bar: 100 μm). E Western blotting analysis of Ecadherin, MKRN1, SNIP1, and TGFβ1 protein expression in intestinal tissues of the two groups of mice. F MKRN1 facilitates the TGFβ signalling via ubiquitination and degradation of SNIP1, thereby promoting EMT in CRC cells. *P < 0.05, *P < 0.01, * P < 0.001
Incorrect Fig. 7D
MKRN1 promotes tumour proliferation and metastasis in vivo. A Comparative graph showing the number of intestinal lesions in the MKRN1 [+/+] and MKRN1 [f/f ] groups. B Haematoxylin–eosin (H&E) staining of the intestine of both groups of mice (scale bar: 100 μm). C H&E staining of the liver in the two groups of mice (scale bar: 100 μm; scale bar: 20 μm). D IHC staining for Ecadherin, MKRN1, SNIP1, and TGFβ1 in the intestinal tissues of the two groups of mice (scale bar: 100 μm). E Western blotting analysis of Ecadherin, MKRN1, SNIP1, and TGFβ1 protein expression in intestinal tissues of the two groups of mice. F MKRN1 facilitates the TGFβ signalling via ubiquitination and degradation of SNIP1, thereby promoting EMT in CRC cells. *P < 0.05, *P < 0.01, * P < 0.001
The correction does not compromise the validity of the conclusions and the overall content of the article. The original article [1] has been updated.
References
Zhang Y, Li Q, Liu H, et al. MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation. J Exp Clin Cancer Res. 2023;42:219. https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-023-02788-w.
Author information
Authors and Affiliations
Corresponding authors
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
The online version of the original article can be found at https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-023-02788-w.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Zhang, Y., Li, Qs., Liu, Hl. et al. Correction: MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation. J Exp Clin Cancer Res 44, 4 (2025). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-024-03265-8
Published:
DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13046-024-03265-8