Table 1 Clinical parameters for MeD-seq on ALD-related liver disease
|  | Liver tissue (n = 46) | cfDNA (n = 42) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Group | Cirrhotic HCC | Cirrhosis | Non-cirrhotic HCC | Non-cirrhotic liver disease | *Benign hepatic lesions | Late-stage HCC | Early-stage HCC | Cirrhosis | Healthy individuals |
N | 6 | 15 | 8 | 10 | 7 | 10 | 10 | 12 | 10 |
Age, median | 67 | 54 | 67 | 47 | 46 | 71 | 71 | 65 | 52 |
Gender, male | 5 (83.3%) | 10 (66.7%) | 5 (62.5%) | 7 (70.0%) | 1 (14.3%) | 9 (90.0%) | 9 (90.0%) | 12 (100%) | 5 (50.0%) |
Cirrhosis | 100% | 100% | 0% | 0% | 0% | 100% | 100% | 100% | 0% |
BCLC-Stage | |||||||||
 Early-stage/BCLC 0-A | 4 (66.7%) | NA | 4 (50.0%) | NA | NA | 0 | 10 (100%) | NA | NA |
 Intermediate/BCLC B | 2 (33.3%) | NA | 4(50.0%) | NA | NA | 8(80.0%) | 0 | NA | NA |
 Late-stage/BCLC C-D | 0 | NA | 0 | NA | NA | 2 (20.0%) | 0 | NA | NA |