Fig. 2

Selection of DMRs from MeD-seq results using IGV software. MeD-seq was conducted on DNA from cirrhotic HCC (red, n = 6) and cirrhotic (blue, n = 15) liver tissues. The DNA methylation profiles of selected genes, as illustrated by IGV software, are displayed. Quantitative methylation specific PCR (qMSP) primers and probes are designed and targeted on these specific hypermethylated regions for the 11 DMMs