Fig. 3

Clonogenic survival of SEC cell lines in different concentrations of SN-38 and rucaparib. A), C), E), G), cells were cultured with continuously in the indicated drug concentrations for 6–9 days, stained and counted. Error bars, mean \(\:\pm\:\) SEM of five independent experiments. B), D), F), H), combination index (CI) for the SN-38 + rucaparib drug combination in SEC cell lines. Different shapes indicate results from each of 3–5 independent experiments