Table 2 Expression patterns of key MiRNAs in hematological malignancies
From: MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications
Hematopoietic Malignancy | Upregulated miRNAs | Downregulated miRNAs |
|---|---|---|
Acute Lymphoblastic Leukemia (ALL) | miR-21, miR-155, miR-181a | miR-34a, miR-126, miR-150 |
Acute Myeloid Leukemia (AML) | miR-10b, miR-21, miR-155, miR-181a | miR-34a, miR-29b, miR-223 |
Chronic Lymphocytic Leukemia (CLL) | miR-21, miR-155 | miR-15a, miR-16-1, miR-34a |
Chronic Myeloid Leukemia (CML) | miR-21, miR-181b | miR-30a, miR-223 |
Diffuse Large B-Cell Lymphoma (DLBCL) | miR-17, miR-21, miR-155, miR-222 | miR-34a, miR-144, miR-181a |
Hodgkin Lymphoma (HL) | miR-21, miR-155, miR-210 | miR-26a, miR-125b, miR-150 |
Multiple Myeloma (MM) | miR-21, miR-221, miR-222, miR-223 | miR-29b, miR-34a, miR-125b, miR-155 |