Fig. 1
Expression of oncogenic KrasG12V, inactivation of Trp53 and stabilization of Ctnnb1 promotes tumorigenesis in KP and KPC mice. A Schematic representation of tamoxifen (TAM) induced KP and KPC mouse models. B Representative images of H&E staining of paraffin sections from lungs in KP, KPC, and liver metastasis in KPC including different growth patterns (papillary, acinar, solid). Scale bars represent 2.5 mm in full size (1x) images and 100 μM in 25 × images, respectively. KP (n = 5) and KPC (n = 5)