Fig. 1

Graphic representation of liquid biopsy markers and sources for cancer detection. Liquid biopsy markers encompass circulating tumor cells, extracellular vesicles, tumor-derived microRNAs, and microbial cell-free DNA derived from the microbiota, which can be utilized to extrapolate cancer-associated microbiota signatures. These markers are released and detectable in various bodily fluids, including blood, urine, saliva, or stool (created with BioRender.com)