Fig. 1

CTC detection in advanced PC patients. CTCs were analysed from blood samples of PC patients with AVPC, NEPC, DNPC or mHSPC with CellSearch or AdnaTest; CTCs were defined by positive CK staining and absent CD45 staining in CellSearch and by detection of epithelial or adenocarcinoma markers in AdnaTest; A: CTC count of individual samples per group, red line indicates the group median; B: representative images of CTCs detected by CellSearch; C: CTC positivity, median CTC count and range determined per group by CellSearch; D: Venn diagram illustrating the number of CTC positive samples in parallel CellSearch and AdnaTest analysis; E: comparison of the percentage of CTC positive samples between the two enrichment methods and the four patient groups, CS-Cellsearch