Fig. 4
From: o8G-modified circKIAA1797 promotes lung cancer development by inhibiting cuproptosis

circKIAA1797 significantly promotes lung cancer progression in vivo. (A) qPCR was performed to detect the efficiency of stable silencing of circKIAA1797 in lentivirus-infected A549 cells. (B) A subcutaneous tumour formation assay in nude mice was performed using a cell line in which circKIAA1797 was stably silenced. (C and D) Tumour size in nude mice and the statistical results. (E to L) Immunohistochemical analysis of Ki67, RhoA, Cyclin D1, and Bcl2 protein expression in nude mouse tumours and quantitative analysis of the results