Fig. 1
High expression of TRAF7 is closely associated with poor prognosis in glioma. A The expression of TRAF7 mRNA was quantitatively analyzed between the glioma tumor site and normal brain tissues based on TCGA database. B-C Kaplan–Meier survival and ROC curves using TCGA. D-E Kaplan–Meier survival curves and ROC for predicting the 1-, 3- and 5-year overall survival (p < 0.0001) in CCGA. F The Nomogram model was built to analyze prognostic factors in 1-, 3-, and 5-year OS of glioma patients. G Decision curve analysis (DCA) for the clinical benefits and application of the nomogram. H-J Calibration curves of the nomogram model for 1-year, 3-year, and 5-year OS. K TRAF7 expression were examined by qRT-PCR in six glioma cell lines. L The knockdown efficiency of TRAF7 mRNA in Hs683 and U251 cells. M The protein expression of TRAF7 was conducted by western blot. N–O TRAF7 protein expression was quantified in Hs683 and U251 cells. Data are presented as the mean ± SD