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Retraction Note: Metformin-repressed miR-381-YAP-snail axis activity disrupts NSCLC growth and metastasis
Journal of Experimental & Clinical Cancer Research volume 44, Article number: 73 (2025)
Retraction Note: J Exp Clin Cancer Res39, 6 (2020)
The Editor in Chief has retracted this article. After publication, a number of serious image integrity issues were raised, including but not limited to:
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numerous overlap in gels and blots which are meant to represent different conditions or proteins.
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undeclared splicing in figure 1M.
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repetitions within an image representing histological tissues in Figure 9G.
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partial overlap between panels in supplementary figures 3E and 4D.
The authors were not able to provide an acceptable explanation. Therefore the Editor has lost confidence in the data and the conclusions of this article.
Author Jiwei Guo disagrees with this retraction. All other authors did not respond to correspondence from the publisher regarding this retraction.
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The online version of the original article can be found at https://doi.org/10.1186/s13046-019-1503-6.
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Jin, D., Guo, J., Wu, Y. et al. Retraction Note: Metformin-repressed miR-381-YAP-snail axis activity disrupts NSCLC growth and metastasis. J Exp Clin Cancer Res 44, 73 (2025). https://doi.org/10.1186/s13046-025-03331-9
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DOI: https://doi.org/10.1186/s13046-025-03331-9