Fig. 6
Integrative methylation and expression analysis. The starburst plot showed results of the integrative analysis of promoter methylation and transcriptomic data in CIMP vs. LOW PM cell lines. x and y axes represented the |log10(p-value)| of methylation and the |log10(p-value)| of expression (A), respectively. Canonical pathways (CP) enriched by hyper-methylated and down-regulated genes in CIMP vs. LOW PM cell lines were identified by IPA core analysis (B)