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Table 3 Summary table of baseline clinical characteristics and biomarker scores for the cohort used for whole-genome transcriptomic analysis

From: Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

 

EBRT—Hypo.; 60 Gy, 20 fractions (n = 91)

EBRT—HDR boost; 37 Gy, 15 fractions with a 12.5–15 Gy HDR brachytherapy boost (n = 214)

EBRT—Conv.; 74 Gy, 37 fractions) (n = 127)

Age (years) – median (min, max)

68 (51, 82)

66 (46, 79)

71 (53, 79)

Missing

1

1

1

PSA (ng/ml) – median (min, max)

19.3 (1.9, 180.0)

20.8 (3.6, 225.0)

17.5 (1.8, 234.0)

Missing

5

5

1

ISUP grade ( n )

 1

2

5

6

 2

28

39

40

 3

22

68

30

 4

13

36

14

 5

26

66

36

T stage ( n )

 1

6

6

0

 2

31

66

8

 3

51

139

111

 4

2

1

0

Missing

1

2

8

Tumor (%) – median (min, max)

50 (5, 95)

65 (5, 100)

60 (5, 100)

ADT duration (months) – median (min, max)

27 (2, 39)

18 (3, 99)

24 (3, 36)

Missing

0

4

2

CAPRA risk score (n)

 Low (0 – 2)

0

0

2

 Intermediate (3 – 5)

17

25

22

 High (6 – 10)

74

189

103

  1. ADT Androgen deprivation therapy, CAPRA Cancer of the Prostate Risk Assessment, Conv Conventional radiotherapy, EBRT External beam radiotherapy, HDR High dose rate, Hypo Hypofractionated radiotherapy, PSA Prostate-specific antigen