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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factors

Fig. 3

Anti-tumor effect of LDB1 knockdown in leukemia mouse model. A Schematic diagram of the vivo experimental design. B Relevant bioluminescence imaging of D18, D25 and D32 days in LDB1 knockdown group and control group. C Biological image of Avg radiance uptake by liver and spleen tissue between two groups. D Histogram shows the bioluminescence signal values for both groups of mice at different time points. E Histogram shows the bioluminescence signal values of liver, and spleen. F Mice in the LDB1 knockdown group exhibited prolonged survival time compared to the control group. G Different sizes and weights of liver and spleen, from sh-NC or sh-Ldb1 mices. H The liver and spleen weights show statistical differences between the two groups. I Representative images of HE staining and IHC staining of mice livers

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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