Fig. 1

Characterizations of LA-CMGL. (a, b) The LA-CMGL and CMGL showed 160–170 nm average particle sizes, and similar morphology (c, d). (e) The stability of LA-CMGL during 7 days incubation with 10% FBS at 4 ℃ and 37 ℃. (f) Gel retardation assay after incubation with mouse serum for 2, 6, 8, 12 and 24 h. (g, h) In vitro release profile of free CPT and CPT in LA-CMGL at pH 4.5, 6.5 and 7.4. Data are mean ± standard deviation (SD)