Fig. 1

ONC201 acts in combination with bevacizumab to significantly impact colorectal cancer growth in vivo. a Final tumor measurements of HT29 human cell colorectal tumors in combination with ONC201 and bevacizumab at the indicated doses after 4 weeks. b Representative fluorescent images. c Final tumor measurements of CRC PDX tumors in SCID mice after 5 weeks. d Representative image of PDX tumors. Bevacizumab is 5 mg/kg every 2 weeks. N = 5