Table 3 Univariate and multivariate analysis of overall survival

Age

 <65

1

 ≥65

1.350(0.706-2.581)

0.364

Gender

 Male

1

 Female

0.910(0.503-1.648)

0.756

Location

 Right

1

1

 Others

0.470(0.259-0.852)

0.013*

0.501(0.272-0.922)

0.026*

Tumor size (cm)

  < 5

1

  ≥ 5

1.801(0.993-3.267)

0.053

AJCC stage

 I + II

1

1

 III + IV

3.106(1.701-5.671)

<0.001*

82.935(13.868-495.998)

<0.001*

T stage

 T1 + T2

1

 T3 + T4

1.662(0.514-5.370)

0.396

N stage

 N0

1

1

 N1 + N2

3.106(1.701-5.671)

<0.001*

2.558(1.355-4.828)

0.004*

M stage

 M0

1

1

 M1

10.801(2.448-47.658)

0.002*

77.710(13.384-451.213)

<0.001*

Differentiation

 Well + Moderate

1

 Poor

2.026(0.627-6.548)

0.238

Vascular invasion

 No

1

1

 Yes

6.188(2.093-18.295)

<0.001*

1.111(0.246-5.019)

0.892

KIF26B

 Low

1

1

 High

5.311(2.360-11.952)

<0.001*

5.621(2.302-13.730)

<0.001*

Ki67

 Low

1

1

 High

2.343(1.254-4.377)

0.008*

1.433(0.718-2.860)

0.307